BDBM416926 (+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl)(cyclopropyl-methylamino)methyl)-2-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::US10329260, Compound 70a

SMILES NCc1cccc(c1)-n1nc(cc1C(=O)Nc1cc(ccc1F)C(NCC1CC1)c1cccc(c1)C#N)C(F)(F)F

InChI Key InChIKey=UXNXMBYCBRBRFD-UHFFFAOYSA-N

Data  2 KI  15 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 416926   

TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human APC using pyroGlu-Pro-Arg-p-nitroaniline-HCl as substrate measured after 5 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed